START POINT

Will be considered new browsers (year 2008 at least).

Prototype is considered as being available by default

IFRAMES

Accessing, changing value of elements of a child iframe from parent page

Example
Lets suppose there is only one frame in page
in the page you call in that frame you have an image with id= img_front.

var im = window.frames[0].document.getElementById('img_front').src;

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